pentobarbital will lessen the extent or influence of ketoconazole by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Small/Importance Mysterious.
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pentobarbital raises toxicity of methoxyflurane by raising metabolism. Contraindicated. Enhanced metabolism of methoxyflurane to nephrotoxic compounds.
pentobarbital will minimize the extent or influence of diazepam intranasal by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep track of. Sturdy or average CYP3A4 inducers may well maximize level of diazepam elimination; therefore, efficacy of diazepam can be reduced.
pentobarbital will reduce the extent or outcome of celecoxib by influencing hepatic enzyme CYP2C9/ten metabolism. Minor/Significance Unfamiliar.
Pentobarbital belongs to a category of medicines referred to as barbiturates which operate by depressing the central nervous program (CNS). Pentobarbital can be utilised off-label to medically induce coma and Management intracranial strain in sufferers with extreme brain injury.
pentobarbital will lessen the extent or influence of sildenafil by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Prevent or Use Alternate Drug. Strong CYP3A4 inducers are envisioned to induce sizeable decreases in sildenafil plasma levels
pentobarbital will decrease the level or impact of theophylline by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on.
pentobarbital will lessen the level or result of verapamil by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on.
pentobarbital will reduce the extent or outcome of estradiol by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on.
pentobarbital raises toxicity of ifosfamide by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check. CYP3A4 inducers may possibly raise the metabolism of ifosfamide to its Energetic alkylating metabolites.
pentobarbital will minimize the extent or influence of check here aprepitant by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep track of.
pentobarbital will reduce the level or outcome of parecoxib by influencing hepatic enzyme CYP2C9/10 metabolism. Use Caution/Monitor.
Period of action, that is linked to the rate at which the barbiturates are redistributed all through the overall body, differs amid people and in the identical individual on occasion.